Claudius Marcellus conquered the Insubres and the Comenses.
The Cenomani nearly always appear in history as loyal friends and allies of the Romans, whom they assisted in the Gallic war (225 B.C.), when the Boii and Insubres took up arms against Rome, and during the war against Hannibal.
In 218 B.C. they were attacked by Hannibal, with whose friends the Insubres they had a long-standing feud, and their chief town (Taurasia) was captured after a three days' siege (Polybius iii.