Already anxieties appear as to the theological verdict upon two of his fundamental views - the infinitude of the universe, and the earth's rotation round the sun.
The responsibilities and anxieties of government unassisted by parliament, and the continued struggle against the force of anarchy, weighed upon him and exhausted his physical powers.
Other anxieties were brought upon him by the burning of his cathedral in 1561, for although Grindal himself is said to have contributed £1 200 towards its rebuilding, the laity of his diocese were niggardly with their subscriptions and even his clergy were not liberal.
But a few weeks before, Mr Drummond, who was Sir Robert Peel's private secretary, had been shot dead in the street by a lunatic. In consequence of this, and the manifold anxieties of the time with which he was harassed, the mind of the great statesman was no doubt in a moody and morbid condition, and when he arose to speak later in the evening, he referred in excited and agitated tones to the remark, as an incitement to violence against his person.
During the trying winter of 1854-55, the suffering he was compelled to witness, the censures, in great part unjust, which he had to endure and all the manifold anxieties of the siege seriously undermined his health, and although he found a friend and ardent supporter in his new French colleague, General Pelissier (q.v.), disappointment at the failure of the assault of the 18th of June 1855 finally broke his spirit, and very shortly afterwards, on the 28th of June 1855, he died of dysentery.
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