Evidence is accumulating which may end in the explanation and perhaps in the prevention of the direst of human woes - cancer itself, though at present inquiry is being directed rather to intrinsic than to extrinsic causes.
But in that gale, the port, the land, is that ship's direst jeopardy; she must fly all hospitality; one touch of land, though it but graze the keel, would make her shudder through and through.
Look now at Stubb; a man who from his humorous, deliberate coolness and equanimity in the direst emergencies, was specially qualified to excel in pitchpoling.
So, too, it is, that in these resplendent Japanese seas the mariner encounters the direst of all storms, the Typhoon.
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