Throw-off meaning

(idiomatic) To confuse; especially, to lose a pursuer.

I never saw her without glasses before, so it threw me off when she got contact lenses.

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(idiomatic) To introduce errors or inaccuracies; to skew.

The dirt in the apparatus threw off the results.

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(UK) A start in a hunt or a race.
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(handball) A throw taken from the centre line which resumes play after each goal and at the start of each period.
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Part or all of this entry has been imported from the 1913 edition of Webster's Dictionary, which is now free of copyright and hence in the public domain. The imported definitions may be significantly out of date, and any more recent senses may be completely missing.
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