Events conspired to ruin him.
When you and a friend get together and make a secret plan, this is an example of a time when you conspire.
When everything seems to go wrong at once, this is an example of a time when it might seem like fate conspires against you.
Origin of conspire
- Middle English conspiren from Old French from Latin cōnspīrāre com- com- spīrāre to breathe
From American Heritage Dictionary of the English Language, 5th Edition