The second Marguerite (1523-1574), daughter of Francis I., was born on the 5th of June, 1523, at St Germain-en-Laye, and, at an age the lateness of which caused lampoons, married Emmanuel Philibert, duke of Savoy, in 1559 Like her aunt and her niece she was a good scholar and strongly interested in men of letters.
Her character, and still more her circumstances, made the pen very unamiably busy with her in her lifetime, the chief of many lampoons being the famous Divorce satirique, variously attributed to Agrippa d'Aubigne, Palma Cayet, and others.
The emperor's rough and severe habits and his rigid administration prompted Antiochene lampoons, to which he replied in the curious satiric apologia, still extant, which he called Misopogon.
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