Main-line definitions

A principal section of a railroad line.
noun
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A group of suburbs of southeast Pennsylvania. The fashionable area was named after the chief railroad line traveling west from Philadelphia.
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A principal and easily accessible vein, usually in the arm or leg, into which a drug can be injected.
noun
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The principal route or line of a railway.
noun
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(fishing) In longline fishing the central line to which the branch lines with baits are attached.
noun
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(slang) A principal vein into which a drug can be injected.
noun
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