Mainline meaning

mānlīn
To inject (an illegal or addictive drug, such as heroin) directly into a major vein.
verb
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To inject a drug intravenously.
verb
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Being in a principal or well-established position.

The mainline churches.

adjective
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The principal road, course, etc.
noun
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Having a principal, prominent, or moderate position or status.
adjective
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(slang) To inject (a narcotic drug) directly into a large vein.
verb
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To inject an illegal or addictive drug, such as heroin, directly into a major vein.
verb
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adjective
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(rail transport) Of or pertaining to the principal route or line of a railway.
adjective
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(rail transport) Of or pertaining to a surface railway as distinct from an underground, elevated or light rail one.
adjective
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To inject (a drug) directly into a vein.
verb
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Origin of mainline