- The definition of resistant is someone or something that fends off or works against.
- An example of someone resistant is a older person who doesn't want to use email; resistant to change.
- An example of something resistant is a bug that isn't dying even though you've sprayed it with pesticide; resistant to spray.
resistant definition by Webster's New World
offering resistance; resisting
Origin: Classical Latin resistens, present participle
a person or thing that resists