conformation Definition
con·for·ma·tion (kän′fôr mā′s̸hən, -fər-)
noun
- Rare a conforming or being conformed; adaptation
- a completed or symmetrical formation and arrangement of the parts of a thing
- the structure or form of a thing as determined by such arrangements; specif., the shape or outline, as of an animal
Etymology: L conformatio < pp. of conformare
conformation Synonyms
conformation
n.
Agreement
compliance, conformity, concord, unison, harmony, affinity, congruity, compatibility, synchronism, adaptation, accordance; see also agreement 1, 2.Shape
structure, formation, symmetrical arrangement; see form 1, symmetry.
conformation Usage Examples
Preposition: of
- molecule: Dynamic conformation of extracellular matrix molecules in aqueous solution.
- protein: Nature of problem: Determination of the spatial conformation of a protein from its amino acid sequence.
- chain: A very high B-factor effectively smears the conformation of that side chain over a large volume which is what you want.
Converse of object
- stabilize: Located at the back of the 30s subunit body where it stabilizes the conformation of the head with respect to the body.
- adopt: The small hydrogen side chain of the glycine amino acids permits the backbone torsion angles to adopt unusual conformations.
- alter: These peptides probably alter the conformation of the phosphodiester chain through a complex interaction with DNA molecule.
- specify: The notation used here conforms with that being proposed for specifying polynucleotide conformation.
Adjective modifier
- helical: Such a mutation could for example be in one of the DNA-binding helices introducing a kink in a normally straight and rigid helical conformation.
- inactive: Hydrolysis of the bound GTP to GDP + P i converts the protein to the inactive conformation.
- molecular: The two molecules are virtually identical in their molecular conformation.
- alternate: Residues with alternate conformations ( using shelx occupancies ) were getting marked as zero occupancy atoms.
- extended: Also, due to their extended conformation, arabinoxylans exhibit a very high viscosity in aqueous solution.
- closed: The closed conformation is usually stabilized by a bound ligand.
Modifies a noun
polymorphism: The method is called single-stranded conformation polymorphism ( SSCP ).
Noun used with modifier
- single-strand: DNA abnormalities were screened by the PCR method and single-strand conformation polymorphism ( SSCP ) analysis.
- backbone: Large changes in backbone conformation during the simulation occur as peaks in the plot.
- protein: They can alter when ligands bind, or when the protein conformation changes.
- chain: The p53 gene mutation was detected by fluorescence-based polymerase chain reaction single-strand conformation polymorphism ( PCR-SSCP ) methods.
- chair: The lowest frequency leads to the chair conformation, and the second lowest to the twist boat.
- energy: Location of the global minimum structure ( lowest energy folding conformation ), however, is a difficult optimization problem.
Browse dictionary entries near conformation
- ‹ conformance
- ‹ conformal
- ‹ conformable
- ‹ conform
- ‹ confocal
- ‹ conflux
- ‹ confluent
- ‹ confluence
- ‹ conflictual
- ‹ conflicting
- conformed copy ›
- conforming ›
- conforming use ›
- conformist ›
- conformity ›
- confound ›
- confounded ›
- confraternity ›
- confrere ›
- confront ›

