Set out from here for Nottingham in 1642 at the outset of the Civil War.
From the outset the prefect of Rome recognized the claims of Damasus, and exerted himself to support him.
This discontent was skilfully fanned by Mithradates the Great at the outset of his Roman campaigns.
The same series of experimental studies led him to conclusions concerning the chief causes of collisions at sea; and these conclusions, though stoutly combated in many quarters at the outset, have since been generally accepted, and were ultimately embodied in the international code of regulations adopted by the leading maritime nations on the recommendation of a conference at Washington in 1889.
The causes of disease may be provisionally classified somewhat as follows, but it may he remarked at the outset that no one of these proximal causes, or agents, is ever solely responsible; and it is very easy to err in attributing a diseased condition to any of them, unless the relative importance of primary and subordinate agencies is discoverable.