- any of a genus (Nicotiana) of chiefly tropical American plants of the nightshade family, with hairy, sticky foliage and long-tubed, white, yellow, greenish, or purple flowers; esp., the species (N. tabacum) now widely cultivated for its leaves
- the leaves of certain of these plants, prepared for smoking, chewing, or snuffing
- products prepared from these leaves; cigars, cigarettes, snuff, etc.
- the use of tobacco for smoking, etc.
Origin of tobaccoSpanish tabaco from uncertain or unknown; perhaps ; perhaps an old Spanish name transferred to the New World plant