Sickle-cell-anemia meaning

A chronic, severe, and sometimes fatal anemia marked by crescent-shaped red blood cells, occurring almost exclusively in black people, and characterized by episodic pain in the joints, fever, leg ulcers, and jaundice. The disease occurs in individuals who are homozygous for a mutant hemoglobin gene.
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An inherited chronic anemia found chiefly among black people, characterized by an abnormal red blood cell (sickle cell) containing a defective form of hemoglobin that causes the cell to become sickle-shaped when deprived of oxygen.
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A chronic, severe, and sometimes fatal anemia marked by crescent-shaped red blood cells and characterized by fever, leg ulcers, jaundice, and episodic pain in the joints. The disease occurs in people who are homozygous for a gene that produces an abnormal form of hemoglobin, and it is found chiefly in people of African descent and in some Mediterranean, Middle Eastern, Central and South American, and South Asian populations.
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A hereditary disease characterized by red blood cells that are sickle-shaped instead of round because of an abnormality in their hemoglobin, the protein that carries oxygen in the blood. Because of their shape, the cells can cause blockage of small blood vessels in the organs and bones, reducing the amount of available oxygen.
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(North America) A disease characterized by sickle-shaped red blood cells.
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