Muggle definitions

(in singular or plural, dated) A marijuana cigarette; a joint.
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(slang) Hot chocolate.
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A person who has no magical abilities.
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(skilled or specialized groups) A person who lacks a skill or is not a member of the group.
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(in geocaching) To remove, deface or destroy a geocache.
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(obsolete) To be restless.
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Origin of muggle

From Harry Potter and the Philosopher's Stone (1997) by J. K. Rowling, from the Harry Potter franchise.