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(idiomatic) Frustrated, annoyed, tired.
Gabriel was fed up with everything.
I'm fed up with moody women today.
I'm so fed up with people making fun of me because I'm different, she said, frowning.
Deidre shook her head and spun away, fed up with deities for the day.
She strode towards the door, fed up with the vamp toying with her.
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