An example of to estrange is for a man to leave his wife.
An example of to estrange is to leave a political party.
The months of bickering estranged her from her family.
Art that is estranged from its historical context.
Origin of estrange
- Middle English estraungen from Old French estrangier from Latin extrāneāre to treat as a stranger, disown from extrāneus foreign strange
From American Heritage Dictionary of the English Language, 5th Edition