In 1904 he delivered at the university of California a course of lectures, the object of which was to illustrate the application of the methods of physical chemistry to the study of the theory of toxins and antitoxins, and which were published in 1907 under the title Immunochemistry.
Amongst these may be mentioned the neutralizing of the toxins in cases of diphtheria, tetanus and poisonous snake-bite; " serum therapeutics "; and treatment by " vaccines."
The irritants may be bacteria and their toxins, or they may be mechanical, chemical or thermic.
At once they proceed to make good their hold on the position they have secured by secreting and throwing out toxins which cause more or less injury to the tissues in their immediate neighbourhood.
This is an increased exudation of fluid from the engorged blood vessels which not only dilutes the toxins, but is supposed to contain substances which in some way act on these living micro-organisms and render them a more easy prey to the polymorpho-nuclear leucocytes (fig.
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