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bioassay Definition

bio·as·say (bī′ō asā)

noun

a technique for determining the power of a drug or other substance by measuring its effects on a test specimen against those of a standard substance

Etymology: bio- + assay

bioassay Usage Examples

Converse of object

  • include: Practical science skills, including bioassay, natural product screening and bioinformatics methodology, are taught to prepare you for the practical research project.
  • conduct: Client Challenge The client conducted a technically complex animal bioassay in-house for a marketed product that was resource-intensive.

Adjective modifier

  • long-term: The Committee made the following comments on each of the long-term bioassays.
  • animal: The different types of models developed to derive risk estimates from animal bioassays were considered to vary greatly in their predictions.
  • long: At present there are no short-term tests that can be used to identify such compounds and long term bioassays in animals are necessary.
  • neonatal: Neonatal mouse bioassay for tumourigenicity: Alternative to the chronic rodent bioassay.
  • dietary: Members agreed that technical grade malathion had been tested in four long-term dietary bioassays in rats and two long-term dietary bioassays in mice.

Modifies a noun

  • datum: Comet assay results were given for 8 organs in the mouse with 208 chemicals for which carcinogenicity bioassay data were available.
  • system: The bioassay systems have also been used in the search for novel activities in extracts of inflamed tissues.
  • method: A range of bioassay methods are now available to assess resistance.

Noun used with modifier

  • carcinogenicity: Comet assay results were given for 8 organs in the mouse with 208 chemicals for which carcinogenicity bioassay data were available.
  • rodent: Neonatal mouse bioassay for tumourigenicity: Alternative to the chronic rodent bioassay.
  • mouse: The mouse bioassay involves inoculating mice with suspect tissue from a cow or sheep.
  • rat: The Committee agreed that there were very limited validation data on the neonatal mouse bioassay and even fewer data regarding the neonatal rat bioassay.
  • term: Long term animal carcinogenicity bioassays are currently in progress.
  • inhalation: The Committee agreed that the negative rat inhalation carcinogenicity bioassay provided additional reassurance with regard to possible site of contact mutagenicity.

Preposition: in

  • rat: It had also been noted that wheezing had been reported as a possible sign of toxicity in one of the earlier bioassay in rats.
  • mouse: Members agreed that technical grade malathion had been tested in four long-term dietary bioassays in rats and two long-term dietary bioassays in mice.
  • animal: At present there are no short-term tests that can be used to identify such compounds and long term bioassays in animals are necessary.

Preposition: of

  • tissue: The bioassays of other tissues from sCJD patients were inconclusive.