- The definition of an antagonist is a person or thing that competes with or goes against another.
Darth Vader is an example of an antagonist to Luke Skywalker.
- a person who opposes or competes with another; adversary; opponent
- a muscle, drug, etc. that acts in opposition to or counteracts another
- One who opposes and contends against another; an adversary.
- The principal character in opposition to the protagonist or hero of a narrative or drama.
- Physiology A muscle that counteracts the action of another muscle, the agonist.
- A drug or chemical substance that interferes with the physiological action of another, especially by combining with and blocking its nerve receptor.
- An opponent or enemy.
- One who antagonizes or stirs.
- (biochemistry) A chemical that binds to a receptor but does not produce a physiological response, blocking the action of agonist chemicals.
- 2001: The calcium antagonists represent one of the top ten classes of prescription drugs in terms of commercial value, with worldwide sales of nearly $10 billion in 1999. — Leslie Iversen, Drugs: A Very Short Introduction (Oxford 2001, p. 41)
- The main character or force opposing the protagonist in a literary work or drama.
- (anatomy) A muscle that acts in opposition to another.
- A flexor, which bends a part, is the antagonist of an extensor, which extends it.
From Latin antagonista, from Ancient Greek ἀνταγωνιστής (antagōnistēs, “opponent”) (ἀντί (anti, “against”) + ἀγωνιστής (agōnistēs, “a combatant, pleader, actor”)), from ἀνταγωνίζεσθαι (antagōnizesthai, “antagonize”).