The quality of being changeable; mutability.
The vicissitude of fortune.
Unpredictable changes or variations that keep occurring in life, fortune, etc.; shifting circumstances; ups and downs.
A difficulty that is likely to occur, esp. one that is inherent in a situation.
Regular change or succession from one thing to another, or one part of a cycle to the next; alternation; mutual succession; interchange.
(often in the plural) A change, especially in one's life or fortunes.
Vicissitude is an unpredictable change in your luck or circumstances.
An example of vicissitude is when you have a great job but then you lose your great job.
Origin of vicissitude
- Latin vicissitūdō from vicissim in turn probably from vicēs pl. of vix change weik-2 in Indo-European roots
From American Heritage Dictionary of the English Language, 5th Edition