However, there is a difference in the way that the male hormone androgen is metabolized (processed) between the sexes.
It is metabolized by plasma cholinesterase (like suxamethonium ).
Irbesartan is metabolized by the liver via glucuronide conjugation and oxidation.
Many oral drugs are metabolized by cytochromes from the P450 family in the liver.
Rather, it stated that hypericum " ...may significantly affect plasma concentrations of any drug that is metabolized by the cytochrome P-450 system.
