Near its mouth are the Grand Rapids.
It is served by the Pere Marquette and the Grand Rapids & Indiana railways.
It is served by the Chicago, Cincinnati & Louisville, the Grand Rapids & Indiana and the Pittsburg, Cincinnati, Chicago & St Louis railways, and by the Terre Haute, Indianapolis & Eastern and the Ohio electric interurban railways.
It is served by the Michigan Central, the Lake Shore & Michigan Southern, the Grand Rapids & Indiana, the Kalamazoo Lake Shore & Chicago, and the Chicago Kalamazoo & Saginaw railways, and by interurban electric lines.
It is served by the Pere Marquette, the Grand Rapids & Indiana and the Manistee & North-Eastern railways, and by steamboat line to Chicago and other lake ports.