Disease Definition
 dĭ-zēz 
  diseased, diseases, diseasing
  
    noun
  
 Any departure from health; illness in general.
 Webster's New World 
A particular destructive process in an organ or organism, with a specific cause and characteristic symptoms; specif., an illness; ailment.
 Webster's New World 
Any harmful or destructive condition, as of society.
 Webster's New World 
Lack of ease; trouble.
 American Heritage 
Synonyms: 
  
    verb
  
 To cause disease in; infect or derange.
 Webster's New World 
1590, Edmund Spenser, The Faerie Queene, II.ii.
 Mote he soft himselfe appease, / And fairely fare on foot, how euer loth; / His double burden did him sore disease.
 Wiktionary 
Other Word Forms of Disease
Noun
Singular:
 diseasePlural:
 diseasesOrigin of Disease
-  
Middle English disese, from Anglo-Norman desese, disaise, from Old French desaise (dis- + ease). Displaced native Middle English adle, audle (“disease”) (from Old English ādl (“disease, sickness”)), Middle English cothe, coathe (“disease”) (from Old English coþu (“disease”)).
From Wiktionary
 -  
Middle English disese from Old French des- dis- aise ease ease
From American Heritage Dictionary of the English Language, 5th Edition
 
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