To disturb the order, arrangement, or functioning of.
An asteroid impact large enough to derange the climate.
To derange is defined as to unsettle something or to make insane.
An example of to derange is to change the pattern of a child’s day.
An example of to derange is to drive someone crazy.
To upset (normal condition or functioning, as of a bodily organ).
To cause to be psychotic or otherwise severely mentally unsound.
To upset the arrangement, order, or operation of; unsettle; disorder.
To make insane.
Origin of derange
- French déranger from Old French desrengier des- de- reng line (of Germanic origin sker-2 in Indo-European roots)
From American Heritage Dictionary of the English Language, 5th Edition