Wilson-s-disease meaning

wĭl'sənz
A rare hereditary disease caused by a defect in the body's ability to metabolize copper that results in an accumulation of copper deposits in organs such as the brain, liver, and kidneys.
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A disease characterized by abnormal accumulation of copper in the brain, liver, etc.
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(medicine) An autosomal-recessive genetic disorder in which copper accumulates in tissues, resulting in neurological or psychiatric symptoms and liver disease.
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Origin of wilson-s-disease

  • After Samuel Alexander Kinnier Wilson (1877–1937), British neurologist
    From American Heritage Dictionary of the English Language, 5th Edition

Wilson-s-disease Sentence Examples

  • For example, a disorder known as hemochromatosis leads to iron toxicity, while Wilson's disease results in copper toxicity.

  • Severe alterations in copper metabolism occur in two genetic diseases, Wilson's disease and Menkes disease.

  • Children born into families with a history of Wilson's disease should have a blood test for the disease at some point in their second year of life, before symptoms of the disease develop.

  • In addition to a deficiency in blood plasma of a protein known as ceruloplasmin, Wilson's disease is characterized by gold or greenish-gold discolorations of the cornea of the eye known as Kayser-Fleischer rings.

  • The clinical symptoms of Wilson's disease do not appear in young children; however, measurements of serum ceruloplasmin can be taken in children over 12 months of age if a family history of Wilson's disease is a risk factor.

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