Other drugs that have been used to treat JA include methotrexate, sulfasalazine, penicillamine, and hydroxychloroquine.
Furthermore, therapy for these diseases can sometimes induce the disease, Eg penicillamine inducing drug-induced lupus in rheumatoid patients.
After an initial period of treatment with penicillamine, Wilson's disease may be treated with zinc (150 mg oral Zn/day).
It is fatal unless the patient complies with lifelong treatment with penicillamine and zinc oxidase.
The three most common chelating agents are calcium disodium edetate, dimercaprol (BAL), and penicillamine.