Santee definitions

săn-tē'
A member of the eastern branch of the Sioux, comprising the Mdewakanton, Sisseton-Wahpeton, and Wahpekute peoples, with present-day populations in Nebraska, Minnesota, the Dakotas, and Canada.
noun
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River in E S.C., flowing southeast into the Atlantic: 143 mi (230 km)
proper name
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