Sentence Examples

  • For example, sulfonylurea drugs are not FDA approved for use in children with type 2 diabetes due to a lack of clinical studies in pediatric populations, but a physician may prescribe them in an off-label use of the drug.
  • With the sheer number and severity of side effects, trials for FDA approval of Topamax as a weight loss treatment were discontinued; however, many doctors will prescribe Topamax for this off-label use.
  • Other adult type 2 diabetes medications, such as sulfonylureas and meglitinide drugs, which work by increasing insulin production, may be prescribed off-label for pediatric use.
  • Even though Botox has only been approved to treat axillary hyperhidrosis, physicians can legally use Botox "off-label" to treat other affected areas of the body.
  • Kant, R., et al. "The Off-Label Use of Clozapine in Adolescents with Bipolar Disorder, Intermittent Explosive Disorder, or Posttraumatic Stress Disorder."