decarboxylation of levodopa.
At least 70 to 100mg of carbidopa per day should be provided for optimal inhibition of extracerebral decarboxylation of levodopa.
half-life of levodopa (1.5 hrs) is implicated in the development of disabling dyskinesias.
Levodopa, the metabolic precursor of dopamine, relieves the symptoms of Parkinson's disease presumably by being converted to dopamine in the brain.
Medications such as levodopa and carbidopa may be used.