De-novo meaning

dĭ nō'vō, dā
Over again, anew.
adjective
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Once more; anew; again.
adverb
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Anew, afresh, from the beginning; without consideration of previous instances, proceedings or determinations.

De novo kidney transplantation.

De novo prediction of three-dimensional structures for major protein families.

He filed a motion for a de novo hearing.

adjective
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Anew (from the beginning)
adverb
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Origin of de-novo

From the Latin adverb dē novō (“from the new”); from (“from”) + novō, the ablative singular of novus (“new”).