Controlled Substance Definition

kən-trōld
noun
A drug regulated by the Federal Controlled Substances Acts, including opiates, depressants, stimulants, and hallucinogens.
Webster's New World
Any drug whose production, possession, importation, and distribution is strictly regulated or outlawed. These include depressants (such as barbiturates), hallucinogens (LSD, mescaline, and peyote), marijuana, opiates (heroin, morphine, and opium), and stimulants (amphetamines and cocaine). The substances are listed in five categories, or schedules, according to their characteristics and the type and degree of regulation is determined by the category the particular substance is in.
Webster's New World Law

(idiomatic) A drug deemed to be illegal by a government except for very limited professional testing purposes.

Wiktionary

Other Word Forms of Controlled Substance

Noun

Singular:
controlled substance
Plural:
controlled substances

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