sickle cell anemiasickle cell anemia
an inherited chronic anemia found chiefly among black people, characterized by an abnormal red blood cell (sickle cell) containing a defective form of hemoglobin that causes the cell to become sickle-shaped when deprived of oxygen
also sickle cell disease
sickle cell anemia
A chronic, severe, and sometimes fatal anemia marked by crescent-shaped red blood cells and characterized by fever, leg ulcers, jaundice, and episodic pain in the joints. The disease occurs in people who are homozygous for a gene that produces an abnormal form of hemoglobin, and it is found chiefly in people of African descent and in some Mediterranean, Middle Eastern, Central and South American, and South Asian populations. Also called sickle cell disease .