sickle cell anemiasickle cell anemia
an inherited chronic anemia found chiefly among black people, characterized by an abnormal red blood cell (sickle cell) containing a defective form of hemoglobin that causes the cell to become sickle-shaped when deprived of oxygen
also sickle cell disease
sickle cell anemia
A chronic, severe, and sometimes fatal anemia marked by crescent-shaped red blood cells, occurring almost exclusively in black people, and characterized by episodic pain in the joints, fever, leg ulcers, and jaundice. The disease occurs in individuals who are homozygous for a mutant hemoglobin gene. Also called sickle cell disease.