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potentiate Definition

po·ten·ti·ate (pō ten′s̸hē āt′, pə-)

transitive verb -·at′ed, -·at′·ing

to increase or multiply (the effect of a drug or toxin) by the preceding or simultaneous administration of another drug or toxin

Etymology: < L potentia, potency + -ate, infl. by Ger potenziren < potenz < L potentia

potentiate Related Forms
po·ten′·tia′·tor noun po·ten′·tia′·tion noun
potentiate Usage Examples

Object

  • effect: Analysis of the convulsant potentiating effects of lithium in rats.
  • response: Diuretics and other antihypertensive agents: Combination with diuretics or other antihypertensive agents may potentiate the antihypertensive response to Tritace.
  • action: Cr primarily functions by potentiating insulin action, which leads to the normalization of post-prandial glucose levels.
  • ototoxicity: Lasilactone may potentiate the ototoxicity of aminoglycosides and other ototoxic drugs.
  • release: They may also potentiate the release of some anabolic hormones, such as growth hormone.
  • production: It is primarily required for blood sugar management, as it potentiates the production and release of insulin.

Subject

  • administration: The hypotensive effects of nitrates are potentiated by the concurrent administration of sildenafil.
  • hypoxia: Particular caution is advised in severe asthma as this effect may be potentiated by hypoxia and concomitant treatment ( see section 4.5 ).

Preposition: by

  • administration: The hypotensive effects of nitrates are potentiated by the concurrent administration of sildenafil.
  • hypoxia: Particular caution is advised in severe asthma as this effect may be potentiated by hypoxia and concomitant treatment ( see section 4.5 ).

Modifying Another Word

  • also: Other inputs to the fast flexor were also potentiated.
  • strongly: The administration of vasopressors strongly potentiate the neurological effect of the intra-arterial contrast media.
  • theoretically: Mesalazine can theoretically potentiate the side effects of glucocorticoids on the stomach.
  • either: Glimepiride may either potentiate or weaken the effects of coumarin derivatives.