- Irrespective of, regardless of, in spite of.
- She'll never catch up with them, no matter how hard she works.
- It doesn't matter, it's unimportant, it doesn't make any difference.
- It seems that Doug's coat has gone missing. Oh well no matter, we can always buy a new one, now can't we?
- "Did you fail your exam?" "Yes, but no matter. I'll just study harder next time."