a sandwich of cold meats, cheese, and olive salad on a large, round roll: it originated in New Orleans
See muffuletta in American Heritage Dictionary 4
(mŭˌfə-lŏtˈə, -lĕtˈ-)
noun New Orleans
A sandwich made with a large round roll of Italian bread split in half and filled with layers of hard salami, ham, provolone, and olive salad.
Regional Note: The New Orleans muffuletta is one of the few large American sandwiches not made with a long crusty roll. Instead, it is made with a round loaf of Italian bread. The bread's shape and the presence of the olive salad distinguishes the muffuletta from the submarine sandwich. Marian Burros of the New York Times traces the creation of the muffuletta to Salvatore Lupa's Central Grocery in New Orleans in 1910. The sandwich was a favorite lunch for Louisiana farmers on their trips into town.