Destiny wasn't her only granddaughter, but all of the others were in their teens.
Of Spain by Elisabetta Farnese (1692-1766), granddaughter of Ranuccio II.
He said he had a granddaughter who was special and he didn't want her to get stuck doing some sort of manual labor.
Representatives of the royal Stuarts who are senior to the house of Hanover, for Philip, duke of Orleans (brother of Louis XIV.3, married, as his first wife, Henrietta daughter of Charles I., and, as his second, Charlotte, granddaughter and heiress of the princess Elizabeth (daughter of James I.).
On Barbara's death three years later without male offspring, Sigismund (in April 1518) gave his hand to Bona Sforza, a kinswoman of the emperor and granddaughter of the king of Aragon, who came to him with a dowry of 200,000 ducats and the promise of an inheritance from her mother of half a million more which she never got.