Bible four figures representing pestilence, war, famine, and death, whose appearance signals that the end of the world is near: Rev. 6:2-8
See Four Horsemen of the Apocalypse in American Heritage Dictionary 4
plural noun
In the Book of Revelation, four horsemen that personify pestilence, war, famine, and death, sent as harbingers of the end of the world. Also called Four Horsemen.