Pyrin Definition

Pyrin Sentence Examples

• The MEFV gene carries the instructions for production of a protein called pyrin, named for pyrexia, a medical term for fever.

• Research has shown that pyrin has some function in controlling neutrophils, which are the white blood cells that move into an area of the body affected by stress or trauma.

• In a person with a normal immune system, some inflammation may follow stress or trauma, but the pyrin protein is responsible for shutting down the response of neutrophils once they are no longer needed.

• An abnormal pyrin protein associated with FMF may be partly functional but unstable.

• In some instances, the abnormal pyrin itself seems to be "stressed", and loses its ability to regulate the inflammatory response to trauma.