Commercial processors often solve this problem using a heat process called granulation which can degrade nutrients.
This is accomplished by a twofold agency, for while numbers of them are seized upon by the granulation phagocytes, others are broken up and dissolved by the liquid filling the granulation interspaces (Afanassieff).
It is convection of this form that makes the solar granulation that can be seen surrounding the sunspots in the detailed image above.
However, some authors recommend skin grafts or myocutaneous flaps once the wound shows healthy granulation.
Its uniform, coarse granulation allows for complete hydration without the aid of an external diluent.