Germline definition

jûrmlīn
The gamete-producing cells in a sexually reproducing organism, by means of which genetic material is passed on to subsequent generations.
noun
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The collection or sequence of such cells in an individual and all its descendants.
noun
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The gamete-producing cells in a sexually reproducing organism, by means of which genetic material is passed on to subsequent generations.
noun
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The collection or sequence of such cells in an individual and all its descendants.
noun
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Other Word Forms

Noun

Singular:
germline
Plural:
germlines

Germline Sentence Examples

  • The incidence of retinal angioma does not appear to be correlated with specific germline mutations.

  • In the germline DNA, the V genes encoding the antigen combining sites need to combine with the C genes.

  • Our position on the related issues of stem cells research, human cloning and germline modification is presented below.

  • Specifically, in 2% of patients, the mutated TSC gene is not detected in either parent because of germline mosaicism.

  • Many members of Li-Fraumeni families have a germline mutation of the TP53 gene.

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Words near germline in the Dictionary