Down Syndrome Definition

A congenital condition characterized by abnormal chromosomes, mental deficiency, a broad face, slanting eyes, a short fifth finger, etc.
Webster's New World

(chiefly US) Condition caused by a chromosomal excess, whereby the patients bear a certain resemblance to the Mongoloid race, such as a small head and tilted eyelids, and typically have a delay in cognitive ability and physical growth.

  • mongolianism
  • Down's syndrome
  • trisomy-21
  • mongolism

Origin of Down Syndrome

  • Named after John L.H. Langdon-Down (1828-1896), an English physician who described it in the late 1800s. The term was first used in 1961.

    From Wiktionary

  • After John Langdon Haydon Down (1828–1896), British physician

    From American Heritage Dictionary of the English Language, 5th Edition


Find Similar Words

Find similar words to Down syndrome using the buttons below.

Words Starting With

Words Ending With


Down syndrome