To reduce sharply the population of, as by disease, war, or forcible relocation.
To reduce the population of, esp. by violence, disease, etc.
Origin of depopulate
- Latin dēpopulāri dēpopulāt- to lay waste dē- de- populārī to ravage (from populus people, throng)
From American Heritage Dictionary of the English Language, 5th Edition
- de- + populate