Accompanying the pain there is more or less of nausea, and when the attack reaches its height vomiting may occur, after which relief comes, especially if sleep supervene.
In larger doses colchicum or colchicine acts as a most violent gastrointestinal irritant, causing terrible pain, colic,vomiting, diarrhoea, haemorrhage from the bowel, thirst and ultimately death from collapse.
Later on vomiting occurs.
Great prostration, vomiting and cold, clammy perspiration follow within one to three hours.
Tartar emetic (antimony tartrate) when swallowed, acts directly on the wall of the stomach, producing vomiting, and after absorption continues this effect by its action on the medulla.