seaport on the coast of central Calif., separated from Oakland by an inlet () of the Pacific: pop. 777,000
Origin of San FranciscoSpanish name of old mission there, after Saint Francis of Assisi
- San Franciscan
A city of northern California on a peninsula between the Pacific Ocean and San Francisco Bay. It was founded as Yerba Buena in 1835 near the site of a Spanish presidio and mission built in 1776. The city grew into a major port during the gold rush of 1848, and survived a devastating earthquake and fire in 1906. Today it is the center of a large metropolitan area around San Francisco Bay.
- San Fran·cis′can