In 1510 a second expedition against Malacca was sent out from Portugal under the command of Diogo Mendez de Vasconcellos, but d'Alboquerque retained it at Cochin to aid him in the retaking of Goa, and it was not until 1511 that the great viceroy could spare time to turn his attention to the scene of Siqueira's failure.
Even after the retaking of Jerusalem by the Moslems (1187) the Pisans and Genoese again met in conflict in the East, and performed many deeds of valour.
The fall of the Latin Empire and the retaking of Constantinople by the Palaeologi freed a great part of the Eastern world from the political and religious direction of Rome, and this fact necessarily engaged the diplomacy of Urban IV.
After the retaking of Jerusalem and recovery of the Cross from the Persians in the eighteenth year of his reign, Heraclius called a mixed council at Karin (Theodosiopolis) of Greeks and Armenians under Ezr (Esdras), catholicus, at which the preceding council of Dvin was cursed, its reforms repudiated and the confession of Chalcedon adopted.
They in their turn handed the city over to the French, but the imperial forces succeeded in retaking it by storm (1636).