- The definition of a pick me up is something that cheers a person up, makes him happy or gives him more energy.
An example of a pick me up is a cup of coffee when you are tired.
pick-me-up definition by Webster's New World
Webster's New World College Dictionary Copyright © 2010 by Wiley Publishing, Inc., Cleveland, Ohio. Used by arrangement with John Wiley & Sons, Inc.
Informal an alcoholic drink taken to raise one's spirits
pick-me-up definition by American Heritage Dictionary
A drink, often an alcoholic beverage, taken as a stimulant or a cure for a hangover.