a chronic disease in which there is scattered demyelination of the central nervous system: it may result in speech defects, loss of muscular coordination, etc.
See multiple sclerosis in American Heritage Dictionary 4
noun Abbr. MS
A chronic autoimmune disease of the central nervous system in which gradual destruction of myelin occurs in patches throughout the brain or spinal cord or both, interfering with the nerve pathways and causing muscular weakness, loss of coordination, and speech and visual disturbances.