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lipase Definition

li·pase (pās′, lipās′)

noun

any of a group of enzymes, esp. from the pancreas, that aid in digestion by hydrolyzing fats into fatty acids and glycerol

Etymology: lip(o)- + -ase

lipase Usage Examples

Converse of object

  • call: In acute pancreatitis, elevated amylase levels usually parallel levels of another enzyme called lipase.
  • produce: Bacillus stearothermophilus Thermophilic species which grows at 65 °C; produces lipase and protease.
  • mobilize: Mobilizing lipase ( = hormone-sensitive lipase ) is the enzyme responsible for the breakdown of stored triglyceride during fasting in response to circulating adrenaline.

Adjective modifier

  • pancreatic: Lipids are converted into an coarse emulsion in the stomach, and into a fine emulsion in the duodenum by pancreatic lipases.
  • hormone-sensitive: Mobilizing lipase ( = hormone-sensitive lipase ) is the enzyme responsible for the breakdown of stored triglyceride during fasting in response to circulating adrenaline.
  • gastric: Production of human gastric lipase in the fission yeast.

Modifies a noun

  • inhibitor: The intestinal lipase inhibitor orlistat reduces the uptake of fat from the diet.
  • enzyme: This increases the surface area of fats for lipase enzymes to act upon.
  • level: In acute pancreatitis, lipase levels are very high, often 2 to 5 times normal.
  • activity: By reducing the lipase activity more fat passes through the intestine and is not absorbed.
  • value: Slightly high lipase values may occur in other conditions such as kidney disease, salivary gland inflammation, or peptic ulcer disease.
  • gene: We will explore the requirement of PUFAs for phototransduction in vivo by generating and characterizing mutants of a novel putative DAG lipase gene.

Noun used with modifier

  • lipoprotein: One caveat, tho, is that lipoprotein lipase and HDL production are probably subject to genetic control.
  • enzyme: Human milk contains the enzyme lipase which helps the baby digest milk fat more efficiently.
  • serum: The serum lipase level is more accurate and a better marker for alcoholic pancreatitis.

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