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creatinine Definition

cre·ati·nine (krē atə nēn′, -nin)

noun

the anhydride of creatine, CHNO, found in blood, muscle, and esp. urine, where measurement of its excretion is used to evaluate kidney function

Etymology: Ger kreatinin < kreatin (see creatine) + -ine

creatinine Usage Examples

Converse of object

  • have: Remember that many patients have low serum creatinine initially therefore a good guide to toxicity is a doubling of the initial creatinine.
  • rise: AAR can be an unusually severe form of rejection, presenting with oliguria and rapidly rising serum creatinine.
  • raise: Care with ACE inhibitors is required in the presence of peripheral vascular disease or raised serum creatinine.

Adjective modifier

  • elevated: The retrograde route is preferred for patients presenting less acutely with elevated serum creatinine or pain.
  • normal: Serum urea and electrolytes and creatinine to assess renal function ( but a normal serum creatinine does not rule out obstruction ).
  • high: Low albumin and high creatinine can indicate renal involvement.

Modifies a noun

  • clearance: Like we have to hold hands to discuss creatinine clearance.
  • excretion: The unit of PD excretion and creatinine excretion is mmol/L.
  • kinase: No notable abnormalities in laboratory values associated with treatment were observed except for minor increases in serum concentrations of creatinine kinase.
  • concentration: The values for PD and creatinine concentrations and PDC index listed were the average of four spot urine samples per day in five consecutive days.
  • ratio: Dopamine to creatinine ratios and noradrenaline to adrenaline ratios did not differ significantly between groups.
  • level: Gilbert's syndrome High creatinine levels High urea How many grams of fat is low fat?

Noun used with modifier

  • serum: The outcome was development of end stage renal disease or doubling of serum creatinine.
  • plasma: A specimen of venous blood is also required to estimate plasma creatinine levels.
  • blood: However, eating large amounts of meat may cause short-lived increases in blood creatinine levels.
  • urine: A combination of blood and urine creatinine levels may be used to calculate a " creatinine clearance.

Preposition: in

  • blood: Measurement of creatinine in blood gives a useful guide to how well the kidneys are working.
  • urine: A utility package for the chemical analysis of purine derivatives and creatinine in urine.

Preposition: of

mg/dl: My mother has a creatinine clearance of 13.09 ml/min and serum creatinine of 4.59 mg/dl.