Blom found that on brominating orthoacetamido-acetophenone in presence of water or acetic acid, the bromine goes into the benzene nucleus, whilst in chloroform or sulphuric acid or by use of bromine vapour it goes into the side chain as well.
The a-halogen compounds are obtained by heating styrolene chloride (or bromide) with lime or alcoholic potash; they are liquids which have a penetrating odour, and yield acetophenone when heated with water to 180°.
Related to styrolene is phenylacetylene, C G H 1 C;CH, which results when a-bromstyrolene or acetophenone chloride are heated to 130° with alcoholic potash, or phenylpropiolic acid with water to 120°.
ACETOPHENONE, or PHENYL-METHYL KETONE, C8H8O or C6H5CO.CH3, in chemistry, the simplest representative of the class of mixed aliphatic-aromatic ketones.
When heated with the halogens, acetophenone is substituted in the aliphatic portion of the nucleus; thus bromine gives phenacyl bromide, C6H6CO.CH2Br.